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  • 產(chǎn)品名稱:Lectin,Mannose-Binding,1(LMAN1)(N-Term)Peptide

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Lectin,Mannose-Binding,1(LMAN1)(N-Term)Peptide
詳情介紹:
Blocked Antibody anti-LMAN1 antibody (Lectin, Mannose-Binding, 1) (N-Term) (ABIN2782680)
Characteristics This is a synthetic peptide designed for use in combination with anti-LMAN1 antibody (Catalog #: ARP46613_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alias Symbols: ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58

Protein Interaction Partner: F8,MCFD2,F8,MCFD2

Protein Size: 510
Molecular Weight 54 kDa
Gene ID 3998
NCBI Accession NM_005570, NP_005561
UniProt P49257
Research Area Signaling
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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