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產(chǎn)品詳情
  • 產(chǎn)品名稱:EnhancerofPolycombHomolog1(Drosophila)(EPC1)(MiddleRegion)Peptide

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  • 產(chǎn)品廠商:半導(dǎo)體
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簡單介紹:
EnhancerofPolycombHomolog1(Drosophila)(EPC1)(MiddleRegion)Peptide
詳情介紹:
Blocked Antibody anti-EPC1 antibody (Enhancer of Polycomb Homolog 1 (Drosophila)) (Middle Region) (ABIN2777875)
Characteristics This is a synthetic peptide designed for use in combination with anti-EPC1 antibody (Catalog #: ARP33343_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

Alias Symbols: DKFZp781P2312, Epl1

Protein Interaction Partner: E2F6,TRIM27,ING3

Protein Size: 836
Molecular Weight 93 kDa
Gene ID 80314
NCBI Accession NM_025209, NP_079485
UniProt Q9H2F5
Research Area Chromatin and Nuclear Signaling
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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