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產(chǎn)品名稱:YOD1OTUDeubiquinatingEnzyme1Homolog(S.Cerevisiae)(YOD1)(N-Term)Peptide
產(chǎn)品型號:
產(chǎn)品廠商:半導(dǎo)體
產(chǎn)品文檔:
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簡單介紹:
YOD1OTUDeubiquinatingEnzyme1Homolog(S.Cerevisiae)(YOD1)(N-Term)Peptide
詳情介紹:
Product details
Product details
Blocked
Antibody
anti-YOD1 antibody (YOD1 OTU Deubiquinating Enzyme 1 Homolog (S. Cerevisiae)) (N-Term) (ABIN2790891)
Sequence
VPQSEAGTKA GPAGGRPADT MWRVRCKAKG GTHLLQGLSS RTRLRELQGQ
Characteristics
This is a synthetic peptide designed for use in combination with anti-Yod1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification
Purified
Target details
Target details
Background
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Yod1 may act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Yod1 mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. It is able to cleave both polyubiquitin and di-ubiquitin.
Alias Symbols: 9930028C20Rik, Hshin7
Protein Size: 343
Molecular Weight
37 kDa
Gene ID
226418
NCBI Accession
NM_178691, NP_848806
UniProt
Q8CB27
Application Details
Application Details
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
Handling
Format
Lyophilized
Reconstitution
Add 100?μL of sterile PBS. Final peptide concentration is 1?mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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